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目的 比较DAE、DA两种方案的疗效 ,达CR的疗程和副作用。方法 对初治急性非淋巴细胞白血病(ANLL) 59例 ,分别给予DAE、DA方案化疗 ,并对两种方案的疗效、疗程和副作用进行比较和分析。结果 ①初治ANLLDA方案的CR率 65 5 % ,DAE方案CR率 73 3 % ,两者CR率P >0 0 5 ;②达CR时所需的疗程 ,DA方案1 7疗程 ,DAE方案 1 4疗程 ;③两方案毒副作用大致相似 ,可以耐受。结论 DAE方案并不能提高CR率 ,但可加快CR过程 ,且不增加毒副作用 ,可推广应用。
Objective To compare the curative effects of DAE and DA in two regimens, and to achieve the therapeutic and side effects of CR. Methods 59 patients with newly diagnosed acute non-lymphocytic leukemia (ANLL) were given DAE and DA regimen respectively. The curative effect, course of treatment and side effects of the two regimens were compared and analyzed. Results ① The CR rate of newly diagnosed ANLLDA regimen was 65 5%, the CR rate of DAE regimen was 73 3%, the CR rate of both was P 0 05; ② The course of treatment required for CR was 17 courses of DA regimen and DAE regimen of 14 Course of treatment; ③ two side effects of similar programs can be tolerated. Conclusions The DAE regimen does not improve the CR rate, but it can speed up the CR process without increasing the toxic and side effects and can be widely applied.