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瘦素(Leptin)———由白色脂肪组织分泌的激素,是机体长时间能量贮存的信号。大多数的肥胖者拥有太多的Leptin并伴有Leptin抵抗。血浆Leptin水平随体脂肪量的增加而增高。甘油三酯导致Leptin抵抗。研究体力活动如何降低血浆Leptin水平成为研究者越来越感兴趣的话题。在体脂肪不减少的情况下,一次急性或中等强度的运动不能改变血浆Leptin的水平,但不能排除运动后Leptin产生改变的可能。它与体力活动本身或能量负平衡有关,也与调控运动后的饮食摄入有关。Leptin和运动刺激了肌肉中蛋白激酶(AMPK)的活化,增加了AMPK的含量,提高了胰岛素(Insulin)的敏感性,加强了肌细胞对葡萄糖的摄入。通过增加Leptin外周作用可以促使其更多地进入下丘脑从而更多地发挥其调节体重的功能。
Leptin - A hormone secreted by white adipose tissue that is the signal of long-term energy storage in the body. Most obese people have too much Leptin with Leptin resistance. Plasma Leptin levels increase with increasing body fat mass. Triglycerides lead to Leptin resistance. Investigating how physical activity reduces plasma Leptin levels has become a topic of increasing interest to researchers. In the case of no reduction in body fat, an acute or moderate exercise can not change the level of plasma Leptin, but can not rule out the possibility of post-exercise Leptin changes. It is related to the physical activity itself or energy balance, but also with the regulation of dietary intake after exercise. Leptin and exercise stimulate the activation of muscle protein kinase (AMPK), increase the content of AMPK, improve the insulin (Insulin) sensitivity and enhance muscle cell glucose uptake. By increasing Leptin peripheral effect can promote its more access to the hypothalamus to play more of its function of regulating body weight.