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目的探讨帕金森患者血尿酸检测的临床意义。方法从2013年12月-2015年12月,选取我院67例确诊为帕金森的患者为研究组,并且用MMSE量表测定将其再分为认知障碍组和非认知障碍组;选取同期67例性别年龄都与研究组相匹配的健康人群为对照组,对2组人群均检测空腹血尿酸值,对结果进行统计学分析。结果研究组的血尿酸水平明显低于对照组,且认知障碍组血尿酸水平低于非认知障碍组(P<0.05)。结论帕金森患者血尿酸水平降低,并且其血尿酸高低可能与认知障碍的发生存在相关性。
Objective To investigate the clinical significance of serum uric acid in Parkinson’s patients. Methods From Dec. 2013 to Dec. 2015, 67 patients diagnosed as Parkinson’s disease in our hospital were selected as study group, and were divided into cognitive impairment group and non-cognitive impairment group by MMSE scale. In the same period, 67 healthy subjects whose age and sex matched the study group were taken as the control group. Fasting serum uric acid was measured in both groups, and the results were statistically analyzed. Results The level of serum uric acid in the study group was significantly lower than that in the control group, and the level of serum uric acid in the cognitive impairment group was lower than that in the non-cognitive impairment group (P <0.05). Conclusion The level of serum uric acid in patients with Parkinson’s disease decreased, and the level of serum uric acid may be related to the occurrence of cognitive impairment.