人类乳头瘤病毒(HPV)是最先存电镜下观察到的病毒之一,但迄今有关其生物学特性却知之甚少,已知能引起人类皮肤粘膜的多种疣和良性肿瘤,在已鉴定的40多种型别中,几乎每一类型都与其体内的感染部位和病变性质有关。值得注意的是,已发现某些HPV类型具有致恶变的可能,因此引起了人们的普遍重视。一、HPV及其分型 HPV乃乳多空病毒科(Papovaviridae)的重要成员,属DNA肿瘤病毒,于宿主细胞核内增殖。这组病毒的形态学相似,都是无包膜的二十而体对称型结构,病毒颗粒直径 Human papillomavirus (HPV), one of the first electron microscopy observed viruses, has so far been poorly informed of its biological properties and is known to cause a variety of warts and benign tumors in human skin and mucous membranes, Of the more than 40 types, almost every type is associated with the site of infection and the nature of the lesion in the body. It is worth noting that some HPV types have been found to have the potential to cause malignant transformation and therefore have drawn universal attention. First, HPV and its classification HPV is an important member of the Papovaviridae (Papovaviridae), is a DNA tumor virus, proliferation in the host cell nucleus. Morphology of this group of viruses are similar, are non-enveloped twentieth body symmetrical structure, the virus particle diameter