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目的 为了研究胃癌细胞DNA指数 (DI)、S期细胞百分率 (SPF)及细胞增殖指数 (PI)与胃癌的预后及淋巴结转移的关系。方法 对 4 1例Ⅲ期胃癌蜡块进行制备细胞悬液后 ,采用美国B-D公司生产的FACSCalibur型流式细胞仪进行细胞获取和测量 ,分析软件采用ModfitLT 2 0。结果 DI、SPF、PI与胃癌预后无关 (P >0 0 5) ,DI与胃癌淋巴结转移有关 (P <0 0 5) ,SPF、PI与淋巴结转移无关。结论 DI、SPF、PI与胃癌预后无关 ,DI与胃癌淋巴结转移关系密切 ;DI越高 ,胃癌越倾向于淋巴结转移 ,而不倾向于深部侵润。而SPF ,PI与淋巴结转移无关
Objective To investigate the relationship between gastric cancer cell’s DNA index (DI), S phase cell percentage (SPF) and cell proliferation index (PI) and the prognosis of gastric cancer and lymph node metastasis. METHODS: Forty-one cases of stage III gastric cancer waxes were prepared for cell suspension. The FACSCalibur flow cytometer produced by American B-D Corporation was used for cell acquisition and measurement. The software used was ModfitLT 2 0. Results DI, SPF, and PI were not related to the prognosis of gastric cancer (P > 0.05). DI was associated with lymph node metastasis in gastric cancer (P < 0.05). SPF and PI were not related to lymph node metastasis. Conclusion DI, SPF and PI are not related to the prognosis of gastric cancer. DI is closely related to the lymph node metastasis of gastric cancer. The higher the DI, the more the gastric cancer tends to lymph node metastasis and does not favor deep invasion. The SPF, PI has nothing to do with lymph node metastasis