胰岛素制剂的进步胰岛素的制作方法 1975年以前的胰岛素制剂是通过再结晶来提纯的,制剂中存在的胰岛素原、单脱酰胺胰岛素等杂质可刺激机体产生胰岛素抗体。使用1975年以前的胰岛素患者(每天20单位以上),体内可出现大量的胰岛素原特异抗体,如果转换成高纯度的精制猪胰岛素(MC胰岛素),血液中与抗体结合的总 Progress in Insulin Preparation of Insulin Insulin preparations prior to 1975 were purified by recrystallization. Insulin precursors, monodexamide, and other impurities present in the formulation stimulated the body to produce insulin antibodies. Using insulin pre-1975 patients (20 units per day or more), the body can appear a large number of proinsulin specific antibodies, if converted to high purity refined porcine insulin (MC insulin), the total amount of antibody bound to the blood