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我们以往的工作证实T细胞对造血干细胞增殖分化的调控作用,经特异或非特异性抗原激活的淋巴细胞具有更强的调控活性。为了进一步弄清细胞间相互作用在造血调控中的地位,近年来我们又探讨了B淋巴细胞对造血干、祖细胞增殖调控作用。
Our previous work demonstrated that T cells regulate the proliferation and differentiation of hematopoietic stem cells, and lymphocytes activated by specific or nonspecific antigens have stronger regulatory activity. In order to further understand the role of cell-cell interactions in hematopoietic regulation, we have also explored the role of B-lymphocytes in regulating the proliferation of hematopoietic stem and progenitor cells in recent years.