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[目的]了解如皋市金婚夫妇代谢综合征(MS)患病的特点及与后天环境因素的相关性。[方法]对如皋市金婚夫妇进行随机抽样调查,内容包括MS相关指标:血压、体质指数、血脂及血糖(含空腹及餐后血糖)等;后天环境因素:文化水平、经济收入、有无医疗保险、煅炼习惯、烟酒指数、有无心脑血管卒中及饮食清淡程度等;通过HOMA-IR公式计算胰岛素抵抗(IR)程度。对照组为同年龄段长期丧偶者(男女各200位),分别比较2组以上各项指标的差异。代谢综合征使用中华糖尿病分会(CDS)2004年诊断标准。[结果]金婚组共有587对完成各项测试,总体MS标化患病率为17.97%,低于对照组(27.50%)(P﹤0.05);金婚组在高血压、血糖、血脂异常发生率方面明显低于对照组,经济收入、文化水平、参保比例、饮食清淡程度方面均高于对照组,心脑血管卒中、IR比例降低(P﹤0.05);金婚组双方均患与均未患MS的分别为85对、461对,占总调查数的93.02%。[结论]如皋市金婚老人的MS患病率要明显低于同龄丧偶者,表明良好稳定的婚姻生活是MS可能的保护性因素,这一现象可能与胰岛素抵抗程度、经济文化水平、参保比例、饮食控制意识等有关;金婚夫妇中MS患病呈现出高度的聚集性,可能也与这些后天环境因素有关。
[Objective] To understand the characteristics of the metabolic syndrome (MS) in Rugao golden-couple and its correlation with acquired environmental factors. [Methods] Rugao golden-married couples were randomized to include MS related indicators: blood pressure, body mass index, blood lipids and blood glucose (including fasting and postprandial blood glucose), etc .; acquired environmental factors: educational level, economic income, with or without medical treatment Insurance, calcining habits, tobacco and alcohol index, the presence or absence of cardio-cerebral vascular stroke and light diet, etc. The degree of insulin resistance (IR) was calculated by HOMA-IR formula. The control group consisted of 200 long-term widowed persons of the same age group (200 men and women respectively), and compared the differences of the above two indexes respectively. Metabolic syndrome using the Chinese Diabetes Branch (CDS) 2004 diagnostic criteria. [Results] A total of 587 pairs of golden wedding groups completed all the tests, and the overall prevalence of MS was 17.97%, which was lower than that of the control group (27.50%) (P <0.05). The incidence rate of hypertension, blood glucose, dyslipidemia (P <0.05). The rates of IR, IR and CVD in both groups were significantly lower than those in the control group (P <0.05). The financial income, education level, proportion of insured and light diet were higher than those in the control group. MS were 85 pairs, 461 pairs, accounting for 93.02% of the total number of investigations. [Conclusion] The prevalence of MS in the golden-married elderly in Rugao was significantly lower than that of widowed in the same age group, indicating that a good and stable marital life is a possible protective factor for MS. This phenomenon may be related to the degree of insulin resistance, economic and cultural level, , Diet control awareness and other related; golden couple in MS showed a high degree of aggregation, may also be related to these acquired environmental factors.