由De Nardi等报道铍所致急性皮炎是一种变态反应,并指出这种变态反应与铍肺炎的病因相关。随后Sterner等提出慢性铍病的发病机制主要是抗原-抗体反应的理论。本文仅据国外文献。对铍病免疫学问题综述如下。 Acute dermatitis caused by beryllium is an allergic reaction reported by De Nardi et al., Pointing out that this allergy is related to the cause of beryllium pneumonia. Sterner later proposed the pathogenesis of chronic beryllium disease mainly antigen-antibody reaction theory. This article only based on foreign literature. The immunological problems of beryllium are summarized as follows.