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本研究以老龄（１８月龄）小鼠为实验对象，对补肾的右归饮、健脾的四君子汤、活血的桃红四物汤对免疫功能的影响作对比研究。结果表明：老年对照组Ｔ、Ｂ淋巴细胞转化（淋转）、ＯＫＴ＿３细胞均明显低于成年（３月龄小鼠）对照组。经喂中药４周后，活血化瘀组、健脾益气组Ｔ、Ｂ淋转明显高于老年对照组；补肾益精组Ｔ、Ｂ淋转没有明显变化，ＯＫＴ３细胞明显低于老年对照组。这一结果提示：补肾益精方对衰老或肾虚状态下的免疫机能似乎与活血化瘀方、健脾益气方有不同的作用。
In this study, aged (18 months old) mice were used as experimental subjects to compare the effect of kidney-reducing Zuoguiyin, Jianpi Sijunzi Decoction and Huoxue Taohong Siwu decoction on immune function. The results showed that T- and B-lymphocyte turnover and OKT3 cells were significantly lower in the old control group than in the adult (3-month-old mice) control group. After 4 weeks of Chinese medicine, the T and B levels in the blood circulation group and the spleen and Qi group were significantly higher than those in the old control group; there was no significant change in the T and B lymph exchange in the Bushen Yijing group, and the OKT3 cells were significantly lower than the old controls. . This result suggests that the immune function of Bushen Yijing Fang on aging or kidney deficiency status seems to have different effects on promoting blood circulation and removing blood stasis and strengthening spleen Qi.