肝肾综合征是指由严重肝脏病变引起的功能性肾功能衰竭。临床上以少尿或无尿、氮质血症为特征。尸检时肾脏一般无器质性组织学改变。“肝肾练合征”在30年代首先用于描述胆道梗阻手术后并发肾功能衰竭的患者,其后人们用于描述具有肝肾二脏同时受损的任何疾病,如休克、系统性红斑狼疮等。近年来不少作者对肝肾综合征作了大量研究,多数学者认为,肝肾综合征是由进展性肝病引起的肾功能衰竭,而肾脏的功能及形态变化是继发于肝脏损害,肾脏本身并无原发性实质性损害,而是继发于肾血管灌注不足的功能性改变。 Hepatorenal syndrome refers to functional renal failure caused by severe liver disease. Clinically oliguria or anuria, azotemia is characterized. At the time of autopsy, there was no organic histological changes in the kidneys. In the 1930s, “liver and kidney practice syndrome” was first used to describe patients with renal failure after biliary obstruction surgery. Later, people used to describe any disease with both liver and kidney diarrhea, such as shock, systemic lupus erythematosus Wait. In recent years, many authors made a large number of studies on hepatorenal syndrome, most scholars believe that hepatorenal syndrome is caused by progressive liver disease, renal failure, and renal function and morphological changes are secondary to liver damage, the kidney itself No primary substantive damage, but secondary to renal vascular insufficiency of functional changes.