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目的总结手术治疗中央型非小细胞肺癌(NSCLC)的临床效果。方法回顾性分析160例中央型NSCLC患者的临床资料。术前均经纤维支气管镜检查,病理确诊。其中,肿瘤位于主支气管11例,肿瘤侵及叶支气管开口35例。结果常规肺叶切除术100例,支气管袖状肺叶切除29例,全肺切除31例。术后未发生支气管胸膜瘘的并发症。149例获得随访8~72个月;手术切除病例的1年生存率86.8%,3年生存率45.8%,5年生存率24.5%。结论手术是治疗中央型NSCLC的主要手段。手术方式应依据支气管受肿瘤侵及的程度和患者肺功能情况选择常规肺叶切除、袖状肺叶切除或全肺切除术。
Objective To summarize the clinical effect of surgical treatment of central non-small cell lung cancer (NSCLC). Methods The clinical data of 160 patients with central NSCLC were retrospectively analyzed. Preoperative bronchoscopy, pathological diagnosis. Among them, the tumor located in the main bronchi in 11 cases, tumor invasion and bronchial openings in 35 cases. Results 100 cases of conventional lobectomy, bronchial sleeve lobectomy in 29 cases, pneumonectomy in 31 cases. No postoperative complications of bronchopleural fistula occurred. One hundred and ninety-nine patients were followed up for 8 to 72 months. The 1-year survival rate was 86.8%, the 3-year survival rate was 45.8%, and the 5-year survival rate was 24.5%. Conclusion Surgery is the main treatment for central NSCLC. Surgical approach should be based on bronchial tumor invasion and the degree of lung function in patients with conventional lobectomy, sleeve lobectomy or pneumonectomy.