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1985年3月～1992年4月间由Curie研究所收治经病理学证实的晚期或复发性宫内膜癌Ⅱ期49例,患者状况评分为≥2分(WHO),年龄75岁以下,预期存活8周,无主要器官功能衰竭(骨髓、肝、肾、心),病史中无第二原发病灶。 评估内容包括病史和查体、全血计数、血清电解质和肝、肾功能。放射自显影测定病变程度和大小。每4周做1次阶段性的病史采取和查体,以此做再评估。每疗程开始前要有血液和肾功能化验(白细胞计数>3000/mm~3,中性白细胞计数>1500/mm~3,
Between March 1985 and April 1992, 49 patients with stage II advanced or recurrent endometrial cancer confirmed by pathology were treated by Curie Institute. The patients’ condition score was ≥2 points (WHO), under the age of 75, Survival 8 weeks, no major organ failure (bone marrow, liver, kidney, heart), no second primary disease in history. Assessment includes medical history and physical examination, whole blood count, serum electrolytes and liver and kidney function. Autoradiography was used to determine the extent and size of lesions. Every 4 weeks to do a phased history and physical examination, in order to re-evaluate. Blood and renal function tests (leukocyte count> 3000 / mm ~ 3, neutrophil count> 1500 / mm ~ 3,