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目的了解新疆伊犁地区人及家畜贝氏柯克斯体(Coxiella burnetii,Cb,俗称Q热立克次体)血清流行概况。方法采用WHO推荐的间接免疫荧光(IFA)方法检测人及家畜血清中的Q热病原体-贝氏柯克斯体特异IgG、IgM抗体。结果 24份门诊收集的不明发热患者血清中,4例为急性感染,2例为慢性感染或恢复期。85只动物调查结果显示,当地Q热感染主要为羊群,在检测山羊中,75.44%的动物IgMⅠ相抗体阳性,57.89%动物为IgGⅠ相抗体阳性。11.76%(10/85)动物有急性感染,2.35%(2/85)有慢性感染或在感染恢复期。结论新疆伊犁地区人及家畜普遍存在贝氏柯克斯体感染。有必要对该地区Q热进行更加深入的调查研究及采取必要的预防控制措施。
Objective To understand the prevalence of human and livestock Coxiella burnetii (Cb) in Xinjiang Yili region. Methods Serum Q and Q, the specific antibodies to IgG and IgM, were detected by the indirect immunofluorescence (IFA) method recommended by the WHO. Results Serum samples from 24 outpatients with unhealthy fever, 4 were acute and 2 were chronic infection or convalescent. The results of 85 animals showed that the local Q fever was mainly flocks, of which 75.44% of the animals were positive for IgM Ⅰ antibody and 57.89% of the animals were positive for IgG Ⅰ antibody in goat. 11.76% (10/85) animals had acute infection, 2.35% (2/85) had chronic infection or recovered during infection. Conclusion The prevalence of C. cynostella infection in humans and livestock in the Ili region of Xinjiang Autonomous Region. It is necessary to conduct a more in-depth investigation and study on the Q fever in the region and take the necessary precautionary and control measures.