胎儿子宫内输注红细胞(IUT)可有效地治疗胎儿或新生儿溶血病(HDN),但IUT有引起胎儿外伤和并发症导致死亡的危险。有报道披露,给母亲大剂量IVIgG治疗严重Rh(D)同种免疫疾病,可以改善新生儿的临床症状,但花费太大,不能常规用于临床。有人建议在IUT治疗时直接给胎儿IVIgG可能会成为一种较廉价的疗法。本文报告了此研究结果并阐述了IVIgG治疗自身免疫性疾病可能的四种 Fetal intrauterine transfusion of red blood cells (IUTs) is an effective treatment of fetal or neonatal hemolytic disease (HDN), but IUT poses the risk of fetal trauma and complications leading to death. It has been reported that giving mothers high doses of IVIgG for the treatment of severe Rh (D) alloimmune disease can improve the clinical symptoms of newborns, but it is too expensive and can not be routinely used clinically. It has been suggested that administering IVIgG directly to the fetus during IUT therapy may be a less expensive treatment. This article reports the findings and outlines the four possible IVIgG treatments for autoimmune disease