腹部创伤时的致病菌多为内源性肠道菌丛。预防性抗生素应于术前应用,选择的抗生素应针对结肠优势菌,以能有效杀灭厌氧菌(如脆弱类杆菌)和需氧菌(如大肠杆菌)。本文旨在评价氯林可霉素、庆大霉素和磺唑氨苄青霉素能否于术前在手术部位达到有效治疗浓度。对象为腹部枪伤或戳刺伤病人59例。其中28例于术前静脉注射磺唑氨苄青霉素4g,6小时一次;31例静注氯林可霉素600mg,6小时一次,加庆大霉素80mg,8小时一次。开腹后与关腹前各取腹腔液,并对小肠撕裂伤者于 Pathogens when abdominal trauma are mostly endogenous intestinal flora. Preventive antibiotics should be applied preoperatively and antibiotics of choice should be given to colon predominant bacteria to effectively kill anaerobic bacteria such as Bacteroides fragilis and aerobic bacteria such as E. coli. This article aims to evaluate whether clindamycin, gentamicin and fluoxetine can be effective therapeutically at the surgical site prior to surgery. The target was a gunshot wound or stab wound in 59 patients. Among them, 28 cases were given sulforaphane 4g intravenously before operation for 6 hours, 31 cases were intravenously injected with clindamycin 600mg once every 6 hours, gentamicin 80mg once every 8 hours. After laparotomy and abdomen were taken peritoneal fluid, and tear on the small intestine in those