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Objective To study the effect of 1,25-dihydroxyvitamin D3on bone metabolism in diabetic rats and the related molecular mechanism.Methods A total of 45healthy 6-8 weeks old male Sprague Dawley(SD)rats were treated with streptozotocin.The streptozotocin-induced diabetic rats were randomly assigned to diabetic group(DM),low dose vitamin D treated group(LD),and high dose vitamin D treated group(HD).Another 12healthy SD rats were used as normol control group(NC).The rats in NC group and DM group were fed with 0.05
Objective To study the effect of 1,25-dihydroxyvitamin D3 on bone metabolism in diabetic rats and the related molecular mechanism. Methods A total of 45 healthy old 6-8 weeks old male Sprague Dawley (SD) rats were treated with streptozotocin. Streptozotocin-induced diabetic Rats were randomly assigned to diabetic group (DM), low dose vitamin D treated group (LD), and high dose vitamin D treated group (HD) .Annother 12 Heath SD rats were used as normol control group (NC) group and DM group were fed with 0.05