药物联结于特定载体可集中于特定靶组织,但有关以肾为靶的给药系统报道很少。对肾敏感的酶如谷氨转氨酶及磷酸酯酶可与药物联结成前体药物,到肾内重新放出药物,但由于血浆蛋白结合率高,限制了转移入肾。低分子蛋白质将是有吸引力的载体,静脉注射 Drug-linked to a specific vector can be focused on a specific target tissue, but the renal-targeted drug delivery system is rarely reported. Kidney-sensitive enzymes, such as ALT and phosphatase, can bind to drugs as prodrugs and re-release drugs into the kidneys, but metastasis into the kidneys is limited due to the high plasma protein binding rate. Low molecular weight protein will be an attractive carrier for intravenous injection