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本文在11例肥厚性梗阻性心肌病患者中,应用~(99m)锝-红细胞测定左心室喷血分数(LVEF)、五心室充盈时间(Tf)和排空时间(Te),并用超声心动图观察室间隔厚度与左室流出道内径变化,显示静脉注射异搏定后LVEF有所增加,而Tf及Te则明显减少,特别是有家族史者;室间隔厚度变薄,左室流出道明显增大。核心功能仪检查左心功能,而超声心动图直接观察异搏定引起的解剖形态变化,为异搏定治疗肥厚性心肌病的疗效评价提供一定的客观依据。
In this study, 11 patients with hypertrophic obstructive cardiomyopathy were enrolled in this study. Left ventricular ejection fraction (LVEF), five-ventricular filling time (Tf) and emptying time (Te) were measured by 99mTc- Observation of interventricular septum thickness and left ventricular outflow tract diameter changes, showing intravenous verapamil LVEF increased, while Tf and Te were significantly reduced, especially those with a family history of thinner interventricular septum, left ventricular outflow tract obvious Increase. The left and right heart functions are checked by the core function instrument, and the echocardiography is used to directly observe the anatomical changes caused by verapamil, thus providing some objective evidences for evaluating the curative effect of verapamil on hypertrophic cardiomyopathy.