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目的了解2014年贵南县健康儿童麻疹抗体水平,分析该人群免疫状况和疫苗接种效果,为麻疹防控工作提供科学依据。方法选择县级医院及较大的中心卫生院抽取就诊的0~岁、1~岁、3~岁、5~岁、7~14岁组儿童各30名,共150名,采用酶联免疫吸附试验(ELISA)检测血清麻疹Ig G抗体浓度。结果抗体总阳性率为93.3%,各年龄组间差异有统计学意义(P<0.05);保护性抗体总阳性率为62.0%,各年龄组间差异无统计学意义(P>0.05);抗体平均浓度1 273.0 m IU/ml。结论调查发现贵南县麻疹防控形势不容乐观,应在提高麻疹疫苗及时接种率,做好入托、入学新生预防接种证查验工作的基础上,开展健康人群麻疹抗体水平监测工作,同时有计划地开展麻疹疫苗强化免疫活动。
Objective To understand the measles antibody level of healthy children in Guinan County in 2014, and to analyze the immune status and vaccination effect of this population to provide a scientific basis for the prevention and control of measles. Methods A total of 150 children aged 0 ~ 1, 1 ~ 3, 5 ~ 7, and 14 ~ 7 years old were selected from county hospitals and large central hospitals for 150 years. Enzyme linked immunosorbent assay Serum measles Ig G antibody concentration was measured by ELISA. Results The total positive rate of antibody was 93.3%, the difference was statistically significant (P <0.05). The total positive rate of protective antibody was 62.0%, there was no significant difference among all age groups (P> 0.05) The average concentration of 1 273.0 m IU / ml. Conclusions The survey found that the situation of measles prevention and control in Guinan County is not optimistic. On the basis of improving the timely vaccination rate of measles vaccine, carrying out the examination of vaccination certificate for newborn infants and entering new students, the monitoring of measles antibody level in healthy population should be carried out. To carry out measles vaccine to strengthen the immune activities.