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目的 :研究血必净注射液治疗小儿感染性心内膜炎中的疗效及安全性。方法 :择取感染性心内膜炎患儿48例,为我院2014年2年-2016年2月间收治,随机分为两组,对照组(敏感抗生素治疗)与实验组(敏感抗生素+血必净注射液治疗)各24例,对比两组的疗效及安全性差异。结果 :与对照组相比,实验组的治疗有效率明显提高,住院时间明显缩短,血白细胞、CRP、IL-6水平明显降低,P<0.05,但两组的不良反应未见明显差异,P>0.05。结论:采用血必净注射液对小儿感染性心内膜炎进行治疗效果良好,可促进炎症消散,利于患儿康复,值得应用。
Objective: To study the efficacy and safety of Xuebijing injection in the treatment of infantile infective endocarditis. Methods: Forty-eight children with infective endocarditis were selected and admitted to our hospital from February 2014 to February 2016. They were randomly divided into two groups: control group (sensitive antibiotic treatment) and experimental group (sensitive antibiotics + Xuebijing injection treatment) 24 cases each, compared the efficacy and safety differences between the two groups. Results: Compared with the control group, the treatment group significantly improved the treatment efficiency, hospitalization time was significantly shorter, white blood cells, CRP, IL-6 levels were significantly lower, P <0.05, but no significant difference between the two groups, P > 0.05. Conclusion: The use of Xuebijing injection in children with infective endocarditis treatment is good, can promote the dissipation of inflammation, which is conducive to the rehabilitation of children worthy of application.