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目的:观察半夏泻心汤联合西药对难治性胃溃疡的治疗效果及安全性。方法:将近两年内因胃溃疡发作到我院行反复治疗的150例患者纳入本次研究,按照入院时的治疗手段将其分为对照组与观察组,比较两组患者治疗后的症状改善、安全性及疼痛情况。结果:对照组患者治疗1个月后疼痛有所改善,但用药3个月后疼痛出现反复,观察组患者在用药后的第1、3、5个月中疼痛均明显减弱,效果优于对照组(P<0.05),且总有效率(93.3%)相比对照组总有效率(73.3%)更高,同时经远期随访发现,对照组患者50例复发显著高于观察组患者6例复发(P<0.05),差异有统计学意义。结论:半夏泻心汤在西药治疗难治性胃溃疡的基础上巩固了患者的治疗效果,在快速改善患者症状的同时防止疾病的二次复发,同时修复损伤的黏膜组织,提高机体抵御能力,是一种值得推广的治疗方式。
Objective: To observe the efficacy and safety of Banxiaxiexin Decoction combined with western medicine in the treatment of refractory gastric ulcer. Methods: 150 cases of gastric ulcer caused by repeated episodes of gastric ulcer in our hospital in the past two years were included in this study. According to the treatment at admission, the patients were divided into control group and observation group. The symptoms of the two groups were compared after treatment, Safety and pain conditions. Results: The pain of the control group was improved after one month of treatment, but the pain appeared repeatedly after 3 months of treatment. The pain of the observation group was significantly weakened in the first, third and fifth months after the treatment, which was better than the control (P <0.05), and the total effective rate (93.3%) was higher than that of the control group (73.3%). At the same time, the long-term follow-up found that the recurrence rate of 50 patients in the control group was significantly higher than that in the observation group Recurrence (P <0.05), the difference was statistically significant. Conclusion: Banxiaxiexin Decoction consolidates the therapeutic effect of the patients on the basis of Western medicine in the treatment of refractory gastric ulcer, prevents the secondary relapse of the disease while rapidly improving the symptoms of the patients, repairs the damaged mucosal tissue and improves the body’s resistance , Is a worthy promotion of treatment.