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采用单克隆抗体免疫荧光技术，流式细胞术检测，观察了１．５ＧｙＸ射线单次全身照射（剂量率０．２８６Ｇｙ／ｍｉｎ）对小鼠胸腺细胞ＣＤ３分子表达的影响，及胸腺细胞亚群和细胞周期的变化。结果表明，中等剂量照射后，胸腺细胞ＣＤ３分子的百分率明显增高，胸腺细胞ＣＤ３阳性细胞比例为对照组的１７７．６１％。同时，胸腺中ＣＤ４＋及ＣＤ８＋细胞比例亦显著增加，分别为对照的２０２．５％及１６５．８７％。然而，胸腺中ＣＤ４＋、ＣＤ８＋细胞的比例显著降低，为对照组的６８．２８％，与此同时，胸腺细胞周期中Ｓ期细胞比例明显降低，为对照组的５５．１４％。
Monoclonal antibody immunofluorescence technique was used to detect the expression of CD3 in mouse thymocytes by single-body irradiation with 1.5 Gy X-ray (dose rate 0.286 Gy / min) Changes in cell cycle. The results showed that after moderate dose irradiation, the percentage of CD3 molecules in thymocytes was significantly increased, and the proportion of CD3 positive cells in thymocytes was 177.61% in control group. At the same time, the proportion of CD4 + and CD8 + cells in the thymus also increased significantly, which were 202.5% and 165.87% of the control, respectively. However, the percentage of CD4 + and CD8 + cells in the thymus was significantly decreased to 68.28% of that in the control group. Meanwhile, the proportion of S phase cells in the thymocyte cycle was significantly decreased to 55.14% in the control group.