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目的 :了解我院口服性激素类药物的使用情况和变化趋势 ,探讨性激素类药物的合理使用。方法 :以用药金额排序法对我院 2 0 0 0～ 2 0 0 2年度口服性激素类药物的来源、品种和金额等进行归类统计分析并用限定日剂量法对药物使用进行评估。结果 :2 0 0 0～ 2 0 0 2年我院口服性激素类药物用药金额增长了 2 2 .14 % ,DDDs增长了 32 .39% ;用药品种数量及用药金额进口合资药占主导地位 ;雌激素类及孕激素类药物应用呈增长趋势 ,雌激素及类似物用药金额 2 0 0 2年比 2 0 0 0年增长5 4 .6 9% ,孕激素类药物增长 14 .85 % ;用药频度居前的药物为三苯氧胺、安宫黄体酮、雌二醇、克罗米芬等 ;用药金额较大的药物有孕三烯酮、十一酸睾酮、替勃龙、米非司酮、雌二醇等。结论 :应注意口服性激素类药物的合理使用 ,加大国产新药的开发和使用 ,注重药物使用的成本效果比
Objective: To understand the use of oral sex hormones in our hospital and the trend of change to explore the rational use of sex hormones. Methods: The source, variety and amount of oral hormonal drugs in our hospital from 2000 to 2002 were classified and statistically analyzed by the order of the amount of medication and the drug use was evaluated by the defined daily dosage method. Results: The dosage of oral sex hormones in our hospital increased by 22.14% and the DDDs increased by 32.39% from 2000 to 2002. The number and amount of drugs used dominates the import of joint drugs; The application of hormones and progestins showed an increasing trend. The amount of estrogen and analogues used increased by 22.6% in 2002 and 14.45% compared with that in 2000. The frequency of treatment with drugs Among the top drugs are tamoxifen, progesterone progesterone, estradiol, clomiphene, and so on. The drugs with large amount of medication include gestrinone, testosterone undecanoate, tibolone, mifepristone, estradiol Wait. Conclusion: We should pay attention to the rational use of oral hormonal drugs, increase domestic drug development and use, pay attention to the cost-effectiveness of drug use