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结直肠类癌多数是良性的,但有的发展很快,需要积极手术和辅助治疗。结直肠类癌的发展不能单靠病理分期、肿瘤的位置及大小、浸润平面和层次等来评估,DNA倍性的测定有助于了解结直肠肿瘤的生物学特性。作者取31例结直肠类癌的石蜡包埋标本,测定癌细胞核的DNA倍性。为了提高诊断率,每一标本分别自3个不同区域取材。全组31例中,18例男性,平均46岁（28～78岁）。13例无症状,系偶尔发现。26例肿瘤位于直肠,位于阑尾3例和结肠2例。主要症状为便血,盲肠和结肠类癌还有类癌综合征,肿瘤按Kujari分期,Ⅰ期无转移,Ⅱ期有局部转移,Ⅲ期有远处转移。
Most colorectal carcinoid tumors are benign, but some develop rapidly and require active surgery and adjuvant therapy. The development of colorectal carcinoid cannot be assessed solely by the pathological stage, the location and size of the tumor, the infiltrate plane and the level, and the determination of the DNA ploidy can help to understand the biological characteristics of the colorectal tumor. The authors took 31 cases of colorectal carcinoid paraffin-embedded specimens to determine the DNA ploidy of cancer cells. In order to improve the diagnostic rate, each specimen was drawn from 3 different regions. Of the 31 patients in the entire group, 18 were males with an average age of 46 years (28 to 78 years). 13 cases were asymptomatic and were occasionally found. Twenty-six tumors were located in the rectum, 3 in the appendix and 2 in the colon. The main symptoms were blood in the stool, cecum and colon carcinoids, and carcinoid syndrome. The tumors were staged according to Kujari. There was no metastasis in stage I, stage II metastases, and stage III distant metastases.