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目的观察美托洛尔治疗慢性心衰的临床疗效。方法收集我院2010年2月～2012年4月治疗的76例慢性心力衰竭患者给予给予美托洛尔进行治疗。结果 76例患者经过治疗,显效33例,显效率为43.4%,有效38例,有效率为50.0%,无效5例,无效率为6.6%,总有效率为93.3%。患者治疗前后血浆BNP(pg/ml)水平的比较:治疗前BNP水平为(472.18±454.29)pg/ml,治疗后BNP水平为(187.21±175.02)pg/ml,治疗前后血浆BNP水平比较有显著性差异(P<0.05)患者治疗前左室射血分数为(46.41±6.09)%,治疗后左室射血分数为(55.76±6.91)%,治疗后左室射血分数均明显升高,与治疗前比较差异有统计学意义(P<0.05)。结论美托洛尔治疗慢性心衰的临床临床疗效显著,值得推广。
Objective To observe the clinical efficacy of metoprolol in the treatment of chronic heart failure. Methods A total of 76 patients with chronic heart failure treated in our hospital from February 2010 to April 2012 were treated with metoprolol. Results Among the 76 patients, 33 were markedly effective, effective rate was 43.4%, effective rate was 38.0%, effective rate was 50.0%, ineffective rate was 5%, inefficiency rate was 6.6% and total effective rate was 93.3%. The level of plasma BNP (pg / ml) in patients before and after treatment: the level of BNP before treatment was (472.18 ± 454.29) pg / ml, the level of BNP was (187.21 ± 175.02) pg / ml before and after treatment, (46.41 ± 6.09)% before treatment, and left ventricular ejection fraction (55.76 ± 6.91)% after treatment. The left ventricular ejection fraction (LVEF) after treatment was significantly higher than that before treatment (P0.05) Compared with before treatment, the difference was statistically significant (P <0.05). Conclusion Metoprolol treatment of chronic heart failure clinically significant clinical efficacy, it is worth promoting.