论文部分内容阅读
颗粒淋巴细胞增多症(GLPD)是淋巴细胞浆内含有嗜天青颗粒的“颗粒淋巴细胞”在末梢血中增多的疾病的总称。多数情况下,颗粒淋巴细胞是胞浆丰富的大的淋巴细胞(LGL),由于呈单克隆性增多,所以也称为LGL白血病。当含有3个以上嗜天青颗粒淋巴细胞在末梢血中超过2000/mm~3以上时,即可诊断为GLPD。多数呈慢性良性经过,部分呈急性经过而死亡。增多的颗粒淋巴细胞,从表面标记来看,不是属于T细胞,就是属于NK细胞。T-GLPD占70～85%,NK-GLPD占15～30%。
Granulocytosis (GLPD) is a collective term for the disease in peripheral blood in which "granulocytic lymphocytes containing azadite particles in the lymphocyte cytoplasm increase. In most cases, granulocyte lymphocytes are cytoplasm-rich large lymphocytes (LGL), also known as LGL leukemia, due to a monoclonal increase. When containing more than 3 azurophilic granulocyte lymphocytes in peripheral blood more than 2000 / mm ~ 3 or more, you can diagnose GLPD. Most were chronic benign, some died after the passage of an acute. Increased particles of lymphocytes, from the surface marker point of view, not belonging to T cells, or NK cells. T-GLPD accounted for 70 to 85%, NK-GLPD accounted for 15 to 30%.