论文部分内容阅读
目的：观察白细胞介素1α（IL—1α）对兔角膜基质细胞胶原降解作用的影响。方法：应用分光光度法测定体外三维胶原凝胶培养的角膜基质细胞的胶原降解活性。结果：IL—1α以剂量依赖关系促进角膜基质细胞的胶原降解。结论：IL-1α可能是角膜溃疡形成的原因之一。
Objective: To observe the effect of interleukin-1α (IL-1α) on the collagen degradation of corneal stroma cells in rabbits. Methods: The collagen degradation activity of corneal stroma cells cultured in vitro by three-dimensional collagen gel was measured by spectrophotometry. Results: IL-1α promoted collagen degradation in corneal stromal cells in a dose-dependent manner. Conclusion: IL-1α may be one of the causes of corneal ulcer formation.