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1978~1989年收治病毒性肝炎合并真菌感染61例,以肠炎、肺炎为常见,白色念珠菌感染率最高.34.4%内脏真茵感染先有咽部真茵感染.抗生素组19例,激素组9例,抗生素+激素组16例,未用抗生素、激素组17例,抗生素组为激素组的2倍.四组在真菌感染的发病时间以及病死率有非常显著差异(P<0.01),以抗生素+激素组发病最早,≤8天的占68.8%,病死率最高,达93.8%.真菌性腹膜炎,脑膜炎的病死率均>90%,感染隐球菌、毛霉菌、曲霉菌者几乎均死亡.本文分析了各种致病因素的作用,提出在抗生素及/或激素应用7天左右,即加强口咽部真菌检测,有助于早期诊治,降低病死率.
From 1978 to 1989, 61 cases of viral hepatitis complicated with fungal infection were treated with enteritis and pneumonia, and the highest infection rate of Candida albicans was found .34.4% There were 16 antibiotics and hormone groups, 17 without antibiotics and hormones, and 2 times with antibiotics group.The morbidity and mortality of fungal infections in the four groups were significantly different (P <0.01) + The hormonal group had the earliest onset, 68.8% ≤8 days, and the highest case fatality rate was 93.8%. The fatality rates of fungal peritonitis and meningitis were both> 90%. Almost all the patients infected with Cryptococcus, Mucor and Aspergillus died. This article analyzes the role of various risk factors, proposed antibiotics and / or hormones applied about 7 days, which enhance the detection of oropharyngeal fungi, early diagnosis and treatment to help reduce mortality.