目的:探讨移植胚胎数和着床胚胎数与妊娠早期血清β-hCG值的关系。方法:回顾性分析IVF/ICSI新鲜胚胎移植后820个宫内妊娠周期,根据移植胚胎数及移植后35 d B超显示的妊娠囊数分组,比较移植14 d、18 d血清β-hCG水平及其上升幅度。结果:不同移植胚胎数相同妊娠囊数组间比较血清β-hCG差异无统计学意义(P>0.05);妊娠早期血清β-hCG水平:三妊娠囊组>双妊娠囊组>单妊娠囊组,差异有统计学意义(P<0.05);血清β-hCG上升幅度各组比较无统计学意义(P>0.05)。结论:移植胚胎数对妊娠早期血清β-hCG无直接影响;着床胚胎数影响妊娠早期血清β-hCG水平。妊娠囊越多,其hCG水平就越高。 Objective: To investigate the relationship between the number of embryos transferred, the number of embryos implanted and serum β-hCG in early pregnancy. Methods: 820 intrauterine pregnancy cycles after IVF / ICSI fresh embryo transfer were retrospectively analyzed. According to the number of embryos transferred and gestational sac number displayed on the 35th day after transplantation, the serum levels of β-hCG were compared between the 14th and 18th day after transplantation Its rate of increase. Results: The serum β-hCG levels in the first trimester of pregnancy were not significantly different (P> 0.05). The level of β-hCG in the third trimester gestational sac group was higher than that in the second trimester gestational sac group The difference was statistically significant (P <0.05); serum β-hCG increase in each group was not statistically significant (P> 0.05). CONCLUSION: The number of embryos transferred has no direct effect on β-hCG in early pregnancy. The number of embryo implantation affects the level of β-hCG in early pregnancy. The more gestational sac, the higher the hCG level.