论文部分内容阅读
目的了解对细菌性阴道炎患者制定甲硝唑、替硝唑药物联合治疗对病情的干预和控制效果。方法分析对象来自2016-2017年于本院接受诊治细菌性阴道炎患者相关临床资料,从中选取200例,随机数字表将患者分为对照组与观察组(n=100),对应治疗方式分别为单纯甲硝唑治疗、联合替硝唑治疗。在疗程结束后对不同方案干预下患者病情治疗效果和复发情况进行比较。结果以患者病情变化为疗效判断依据,对照组与观察组判定无效例数分别为29例、8例,组间总有效率经过统计学软件处理(P<0.05),提示有意义;对患者进行平均3个月时间随访,期间观察组患者发生复发情况例数明显低于对照组,组间差异用统计学软件处理(P<0.05),提示有意义。结论对细菌性阴道炎患者在考虑治疗干预方案时,可将甲硝唑联合替硝唑作为首选治疗措施,相对于常规单一药物治疗,疗效更为突出且可有效控制治疗后复发情况,值得临床推广。
Objective To understand the intervention and control effect of combination therapy of metronidazole and tinidazole in patients with bacterial vaginosis. Methods The subjects were from the clinical data of patients with bacterial vaginosis from 2016 to 2017 in our hospital. 200 patients were selected. The patients were divided into control group and observation group (n = 100) by random number table. The corresponding treatment methods were Metronidazole alone treatment, combined tinidazole treatment. After treatment at the end of different programs interventions in patients with disease treatment and recurrence of the situation were compared. The results were based on the changes of the patient’s condition to determine the efficacy of treatment, the control group and the observation group to determine the number of ineffective cases were 29 cases, 8 cases, the total effective rate between groups after statistical software processing (P <0.05), suggesting meaningful; The mean follow-up was 3 months. During the observation period, the number of recurrence cases in the observation group was significantly lower than that in the control group. The difference between the groups was statistically analyzed (P <0.05), suggesting a significant difference. Conclusion Metronidazole combined with tinidazole may be the first choice of treatment for patients with bacterial vaginosis when considering treatment intervention. Compared with conventional single drug therapy, metronidazole and tinidazole are more effective and can effectively control recurrence after treatment. Promotion.