Cancer杂志最新研究显示,Ⅳ期结直肠癌患者如果不接受手术切除原发肿瘤能存活更长。自1988年起美国每年Ⅳ期结直肠癌原发肿瘤切除率(PTR)下降,因出现了更新的化疗和生物治疗。美国NCCN指南现在推荐无梗阻、无法切除的Ⅳ期结直肠癌且未进行PTR的患者进行全身化疗。Hu和其同事研究以确定PTR对Ⅳ期结直肠癌患者生存的影响。数据来自NCI监控、流行病学和最 The latest Cancer Research shows that patients with stage IV colorectal cancer survive longer if they do not undergo surgery to remove the primary tumor. Since 1988, the annual IV colorectal cancer primary tumor resection rate (PTR) in the United States has dropped due to the emergence of more advanced chemotherapy and biotherapy. The United States NCCN guidelines now recommend non-obstructive, unresectable, stage IV colorectal cancer and patients who have not undergone systemic chemotherapy for PTR. Hu and colleagues studied the effects of PTR on the survival of patients with stage IV colorectal cancer. Data from NCI surveillance, epidemiology and most