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目的总结无水酒精瘤内注射及减黄手术治疗不能切除的胰头癌的临床经验。方法回顾性分析１９９３年１０月～１９９７年２月２９例不能切除的胰头癌在减黄手术中，于肿瘤内注射无水酒精，术后定期随访。结果减黄手术后１周黄疸逐渐减轻。顽固性腰背痛于短时间内不同程度缓解。肿瘤在术后２月均有所缩小，４例消失。其效果与肿瘤大小、浸润范围呈负相关。结论瘤内无水酒精注射是抑制肿瘤发展的一种辅助措施。此法安全、简便。对原发肿瘤较小、又不能耐受大手术的胰腺癌病人预后较佳。
Objective To summarize the clinical experience in the treatment of unresectable pancreatic head cancer with intratumoral injection of anhydrous alcohol and yellow reduction surgery. Methods Retrospective analysis of 29 cases of unresectable pancreatic head cancer from October 1993 to February 1997 was performed during the course of yellow reduction surgery. Intra-tumor injection of absolute alcohol was performed. Follow-up was performed regularly. Results The jaundice gradually decreased after 1 week of yellow reduction surgery. Intractable low back pain relieved in varying degrees in a short time. Tumors were reduced at 2 months after surgery and 4 patients disappeared. The effect was negatively related to tumor size and infiltration range. Conclusion Intratumoral alcohol injection is an auxiliary measure to inhibit the development of tumor. This method is safe and easy. The prognosis is better for patients with primary tumors with small primary tumors that cannot tolerate major surgery.