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目的探讨双重染色内镜联合检测MG7-Ag抗原对胃癌早期诊断的意义。方法选取2014年1月至2015年6月间因上消化道症状在湖北省宜昌市三峡大学仁和医院就诊的106例患者,患者均接受普通内镜和双重染色内镜检查,根据检测结果分为浅表性胃炎组(35例)、胃溃疡组(33例)、萎缩性胃炎组(20例)和胃癌组(18例),比较各组患者血清MG7-Ag的水平。结果胃癌组患者血清MG7-Ag水平和阳性率明显高于浅表性胃炎组、胃溃疡组和萎缩性胃炎组,差异有统计学意义(P<0.05)。萎缩性胃炎组患者血清MG7-Ag水平和阳性率明显高于浅表性胃炎组、胃溃疡组,差异有统计学意义(P<0.05)。结论双重染色内镜联合检测血清MG7-Ag对提高胃癌早期诊断有重要意义。
Objective To investigate the significance of dual staining endoscopy combined with MG7-Ag antigen in the early diagnosis of gastric cancer. Methods From January 2014 to June 2015, 106 patients with upper gastrointestinal symptoms in Renhe Hospital of Three Gorges University in Yichang, Hubei Province were enrolled in this study. All patients underwent endoscopic and double staining endoscopy. According to the results of the test, Superficial gastritis group (35 cases), gastric ulcer group (33 cases), atrophic gastritis group (20 cases) and gastric cancer group (18 cases). The serum levels of MG7-Ag in each group were compared. Results The serum level of MG7-Ag and the positive rate of gastric cancer group were significantly higher than those of superficial gastritis group, gastric ulcer group and atrophic gastritis group (P <0.05). The serum level of MG7-Ag and the positive rate of atrophic gastritis were significantly higher than those of superficial gastritis and gastric ulcer (P <0.05). Conclusions Dual staining endoscopy combined with serum MG7-Ag can improve the early diagnosis of gastric cancer.