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口腔上皮不仅作为外界环境与宿主之间的一道物理屏障,还具有分泌多种抗菌肽参与天然免疫的作用。其中β-防御素家族具有广谱抗菌的作用,对口腔内的多种细菌有抑制作用,从而保护宿主的健康。本文就β-防御素在牙龈组织的表达及其与牙周可疑致病菌的相互作用关系作一综述。
Oral epithelium not only as a physical barrier between the external environment and the host, but also has the secretion of a variety of antimicrobial peptides involved in the role of natural immunity. Which β-defensin family has a broad-spectrum antibacterial effect on a variety of bacteria in the mouth have an inhibitory effect, thus protecting the host’s health. This review summarizes the expression of β-defensin in gingival tissue and its interaction with suspected periodontal pathogens.