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对芦笋愈伤组织有效成分FP-1、FP-3对S180、EAC、HEp-2的细胞毒作用研究发现：（1）细胞贴壁后4h加入1／10CYD50FP-1及FP-3，使HEP-2细胞浓度维持在4h时的水平不再增加；细胞贴壁后36h加入1／10CYD50的FP-1、FP-3分别使HEp-2细胞的活细胞浓度显著降低。（2）1／10CYD50、2／10CYD50FP-1、FP-3对S180细胞3H-脯氨酸摄取的抑制率为13．3％～57．2％及50．5％～67．1％；对EAC细胞3H-脯氨酸摄取的抑制率为15．3％～22．3％及5．4％～15．5％。（3）1／10CYD50、2／10CYD50的FP-1及FP-3对EAC细胞3H-TdR摄取的抑制率为59．5％～60.8％及62．0％～66．7％。（4）FP-1及FP-3对EAC荷瘤小鼠的生命延长率分别达53．0％及34．7％。文章对细胞毒作用的机理进行了讨论。
The cytotoxic effect of FP-1 and FP-3 on S180, EAC, and HEp-2 of callus from asparagus was found: (1) 1/10CYD50FP-1 and FP-3 were added 4 h after cell attachment to make HEP The level of -2 cells maintained at 4 h was no longer increased; FP-1 and FP-3 with 1/10 CYD50 added 36 h after the adherence of the cells respectively decreased the viable cell concentration of HEp-2 cells. (2) The inhibition rate of 3H-proline uptake of S180 cells by 1/10CYD50, 2/10CYD50FP-1, and FP-3 was 13.3% to 57.2% and 50.5% to 67.1%; The inhibition rate of 3H-proline uptake by EAC cells was 15.3% to 22.3% and 5.4% to 15.5%. (3) The inhibition rate of 3H-TdR uptake of EAC cells by 1/10CYD50 and 2/10CYD50 FP-1 and FP-3 was 59.5%-60.8% and 62.0%-66.7%. (4) The prolongation rates of FP-1 and FP-3 in EAC-bearing mice reached 53.0% and 34.7%, respectively. The mechanism of cytotoxicity was discussed in this article.