生物医学光声显微成像:技术和应用进展

来源 :中国激光 | 被引量 : 0次 | 上传用户:menlyseven
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
光声成像兼具光学成像对比度高和超声成像在深层生物组织中分辨率高等优点,是近年来迅速发展起来的一种生物医学成像模态。光声显微成像(PAM)是光声成像的一种重要实现方式,利用其可以无创提供活体生物组织结构和功能信息的优点,研究人员已开展了临床前和临床应用研究。为了使不同领域的研究人员了解这一快速发展的成像技术,本文综述了光声显微成像的发展现状、最新技术和研究进展。文章首先介绍了PAM的基本原理和典型的系统实现,然后概述了包括空间分辨率、成像深度、扫描方式、信号探测手段和多模态成像等方面的重要研究进展,接着阐述了PAM在生物医学领域的应用现状,最后总结了其未来发展面临的挑战。
其他文献
利用连续光纤激光器进行了800 MPa级和1000 MPa级双相钢的激光拼焊试验,研究了马氏体含量对双相钢焊接接头组织和性能的影响。结果表明,不同马氏体含量双相钢的焊接接头均由全马氏体区和不完全相变区组成。两种焊接接头不完全相变区的宽度和显微硬度的降幅较小,其拉伸断裂位置均位于母材。1000 MPa级双相钢焊接接头在杯突试验中沿不完全相变区直接开裂并扩展,杯突值达到母材的85.0%;800 MPa级双相钢焊接接头则垂直于全马氏体区方向开裂,杯突值达到母材的91.7%,成形性能好。
期刊
采用溶液旋涂法在铟锡氧化物(ITO)电极上制备氧化石墨烯(GO)薄膜作为有机太阳能电池(OPVs)的空穴传输层,通过调控旋涂转速优化了氧化石墨烯薄膜的厚度并研究了膜厚对于器件性能的影响规律。在此基础上,通过紫外臭氧(UVO)处理和热处理等方法进一步提升电池器件的性能。结果表明:在紫外臭氧处理和热处理温度为250 ℃时,所得电池器件的效率最优,达到3.16%,接近于使用经典聚(3,4-乙撑二氧噻吩):聚苯乙烯磺酸(PEDOT:PSS)材料的电池器件水平。这一结果表明具有低成本、可溶液加工以及优异的光透过性等
The development of two-dimensional (2D) transition metal dichalcogenides has been in a rapid growth phase for the utilization in surface-enhanced Raman scattering (SERS) analysis. Here, we report a promising 2D transition metal tellurides (TMTs) material,
期刊
[J. Innov. Opt. Health Sci., Vol. 10, No. 4 (2017) 1730008] The “received date" of this paper should be 4 April 2017 instead of 3 June 2017. The manuscript was originally submitted on 4 April 2017 and the revised version was submitted on 3 June 2017.
期刊
Diabetes is a widespread and serious disease and noninvasive measurement has been in high demand. To address this problem, a power spectral density-based method was offered for determining glucose sensitive sub-bands in the nearinfrared (NIR) spectrum. Th
The silver (Ag) nanowire arrays with regular and uniform size were successfully fabricated inside the nanochannels of anodic aluminum oxide (AAO) template by a simple paired cell method. X-ray diffraction (XRD) and scanning electron microscopy (SEM) resul
期刊
Volatile Fatty Acid number (VFA no.) is one of the parameters indicating the state of quality of Para rubber latex at that particular time. Most factories analyze this parameter using standard analytical method as in ISO 506:1992(E). Nevertheless, this pr
Magnetic nanoparticle plays an important role in biomedical engineering, especially in tumor therapy. In this paper, a new technique has been developed by using the rapid moving magnetic nanoparticle under a low-frequency alternating magnetic field (LFAMF
During the last decade, striking improvements could be achieved for the precise control of deposition processes in optical coating technology. For example, as a consequence of enormous progresses in measurement and computer technology, direct optical moni