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目的:观察应用中心静脉导管胸腔内灌注恩格菲在癌性胸水治疗中的疗效。方法:对30例癌性胸水患者行胸腔内置中心静脉导管,最大限度地排尽积液后,胸腔内进行恩格菲12~20mL灌注治疗,待引流液消失维持48h以上后拔除中心静脉导管,4周后复查。结果:全组总有效率为87%,所有患者未出现严重的全身性毒副反应。结论:恩格菲胸腔内灌注治疗癌性胸水安全、有效。
Objective: To observe the curative effect of intrapleural infusion of Engephi in the treatment of cancerous pleural effusion by using central venous catheter. Methods: Thirty patients with malignant pleural effusion underwent thoracic central venous catheterization to drain the fluid to the maximum extent. After intrapleural injection of 12-20 mL of enflunide, the central venous catheter was removed after more than 48 h of drainage, 4 weeks after the review. Results: The total effective rate was 87% in the whole group. No serious systemic side effects occurred in all patients. Conclusion: Engephi intrapleural infusion of cancer pleural effusion is safe and effective.