伤害性刺激作用于机体引起疼痛的同时,也激动负反馈系统抑制伤害性信息的进一步传入。这正是机体的内源性抗伤害机制。现有的资料表明,这种抗伤害机制主要是通过中枢神经系统来完成的。涉及广泛的中枢结构和不同的递质系统。近年来的研究表明与之有关的中枢递质有5—羟色胺(5-HT)、去甲肾上腺素(NE)、多巴胺(DA)、乙酰胆碱(Ach)以及各种脑啡肽(Enkephalin) Nociceptive stimuli, which cause pain in the body, also excite the negative feedback system to suppress the further transmission of nociceptive information. This is the body’s endogenous anti-injury mechanism. Available data show that this anti-injury mechanism is mainly done through the central nervous system. Involving a wide range of central structures and different neurotransmitter systems. Recent studies have shown that the central neurotransmitters involved are serotonin (5-HT), norepinephrine (NE), dopamine (DA), acetylcholine (Ach) and various enkephalin