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目的:探讨心理干预在先兆流产治疗中的临床疗效及其对内分泌的影响。方法:以先兆流产孕妇施行常规治疗+心理干预80例作为研究组,以先兆流产孕妇施行常规治疗80例作为对照组A,同期无流产病史的早孕妇女80例作为对照组B。以SCL-90症状自评量表评估心理干预对先兆流产孕妇心理状况及疗效的影响,测定各组考地松(Cortisol)、孕酮和β-hCG水平,分析其对先兆流产患者内分泌的影响。结果:先兆流产组与无流产病史组相比,SCL-90评分及Cortisol水平显著增高,孕酮和β-hCG水平显著降低(P<0.05);心理干预组与常规治疗组相比,SCL-90评分及Cortisol水平显著降低,孕酮、β-hCG水平及妊娠成功率显著增高(P<0.05)。结论:心理干预可能通过影响先兆流产患者内分泌机制发挥其治疗作用。
Objective: To investigate the clinical effect of psychological intervention in the treatment of threatened abortion and its effect on endocrine. Methods: Eighty pregnant women undergoing threatened abortion were treated with conventional treatment and psychological intervention. 80 pregnant women undergoing threatened abortion were given routine treatment as control group A, and 80 pregnant women with no history of miscarriage during the same period as control group. The SCL-90 Symptom Checklist 90 was used to evaluate the effect of psychological intervention on the psychological status and therapeutic effect of threatened abortion. Cortisol, progesterone and β-hCG levels in each group were determined and their effects on the endocrine of threatened abortion were analyzed . Results: The levels of SCL-90 and Cortisol were significantly higher and the levels of progesterone and β-hCG were significantly lower in the threatened abortion group than in the abortion group (P <0.05). Compared with the conventional treatment group, the SCL- 90 scores and Cortisol levels were significantly lower, progesterone, β-hCG levels and pregnancy success rate was significantly higher (P <0.05). Conclusion: Psychological intervention may exert its therapeutic effect by affecting the endocrine mechanism of threatened abortion.