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对20例中晚期食管贲门癌患者在内镜下局部注射5-Fu缓释粒子,每周1次,2周为1个疗程,观察治疗前后肿瘤大小变化及狭窄程度缓解情况。结果显示癌肿有不同程度缩小,狭窄程度减轻,无明显毒副作用。内镜下植入5-Fu缓释化疗粒子,对于身体耐受力差或不愿手术治疗的中晚期食管贲门癌患者的癌性狭窄,是一种有效、毒副作用少、耐受性好的姑息治疗方法。
Twenty patients with advanced esophageal and cardiac cancer underwent endoscopic injection of 5-Fu sustained-release particles locally, once a week and 2 weeks as a course of treatment. Changes in tumor size and stenosis were observed before and after treatment. The results showed that the cancer was reduced to varying degrees, reduce the degree of stenosis, no obvious side effects. Endoscopic implantation of 5-Fu sustained release chemotherapy particles for poor or unwilling to surgical treatment of advanced esophageal cancer in patients with cancer stenosis, is an effective, less toxic side effects and good tolerance Palliative treatment.