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应用竞争性蛋白结合法和荧光法分别检测了28例囊尾蚴病患者和28例献血员血浆中cAMP的含量以及血清中组织胺的含量。实验结果表明,囊尾蚴病患者和献血员血浆中cAMP的平均含量分别为20.16±8.41nmol/L和25.40±9.48nmol/L,两者间差异有显著意义(P<0.05);患者和献血员血清中组织胺含量分别为5.3±2.4mg/L和2.7±1.2mg/L,两者差异有非常显著意义(P<0.01)。提示囊尾蚴病患者在发病过程中具有发生Ⅰ型超敏反应的物质基础,因而在采用抗囊虫药物治疗时应配合使用抗过敏药物,以防超敏反应的发生。
The content of cAMP in plasma and the content of histamine in serum of 28 patients with cysticercosis and 28 blood donors were detected by competitive protein binding assay and fluorescence assay respectively. The experimental results showed that the average content of cAMP in patients with cysticercosis and blood donors were 20.16 ± 8.41nmol / L and 25.40 ± 9.48nmol / L, respectively, with significant difference (P <0 .05). The histamine contents in serum of patients and donors were 5.3 ± 2.4 mg / L and 2.7 ± 1.2 mg / L, respectively, with significant difference (P <0.01). Tip cysticercosis patients in the pathogenesis of the occurrence of type I hypersensitivity in the material basis, and therefore the use of anti-cysticercosis drug treatment should be used in conjunction with anti-allergy drugs to prevent the occurrence of hypersensitivity.