目的 :探讨碱血症和肝硬化腹水相关性。方法 :对住院确诊的肝硬化失代偿患者 30 0例(其中发生腹水的 15 2例 )用肝素针筒抽取动脉血 0 5ml立即送检。采用丹麦产ABL4型血气分析仪测定。结果 :低氧血症 ,无腹水组 5 0 9% (75 / 14 8) ,腹水组 92 1% (130 / 15 2 )。酸碱失调 ,无腹水组 4 3 2 % (6 4 / 14 8) ,腹水组 81 6 % (12 1/ 15 2 )。将两组对比 ,血气分析常用指标有明显差异 ,特别是pH >7 4 5 ,无腹水组 4 0 5 % (6 0 / 14 8) ,腹水组 78 6 % (12 1/ 15 2 ) ,P <0 0 1。结论 :碱中毒时血管收缩 ,减少肾血流量和增加门脉阻力 ,发生腹水。另外腹水时隔肌抬高 ,造成通气过度 ,引起pH升高。碱血症和肝硬化腹水是互为因果 ,引起和加重的原因之一 Objective: To investigate the relationship between ascites and cirrhosis and ascites. Methods: A total of 300 patients with decompensated liver cirrhosis who were diagnosed as hospitalized (152 cases in which ascites occurred) were enrolled in the study. Using Danish ABL4 blood gas analyzer. Results: Hypoxemia was 59% (75/148) in ascites group and 92.1% (130/152) in ascites group. Acid-base dysfunction was found in 432% (64/148) in ascites-free group and 81.6% (12 1/152) in ascites group. There were significant differences between the two groups in the common indexes of blood gas analysis, especially pH> 7.45, ascorbic acid group 45.0% (60/148), ascites group 78.6% (12 1/152), P <0 0 1. Conclusions: Vasoconstriction during alkalosis, decreased renal blood flow, increased portal resistance, and ascites. In addition, ascites elevation muscle, causing hyperventilation, causing the pH increased. Alkalosis and cirrhosis of the ascites are each causal, cause and aggravate one of the reasons