本文合成了三种具有不同取代基的铁卟啉配合物,其中氯化四—(4—羟基—3—甲氧苯基)卟啉铁(Ⅲ)是迄今未见报道的新化合物。用它们分别与硫醇化合物和氧一起,构成了新型的细胞色素P—450的模拟体系。实验表明,这些体系具有显著的吸氧活性并能在常温常压下将苯一步氧化为苯酚。文中还对结构与性能之间的关系进行了探讨。在实验的基础上,对羟化机制提出了初步的设想。 In this paper, three iron porphyrin complexes with different substituents were synthesized. Among them, iron (Ⅲ) tetrakis (4-hydroxy-3-methoxyphenyl) porphyrin was a new compound which has not been reported so far. They were used with thiol compounds and oxygen, respectively, to form a novel cytochrome P-450 simulation system. Experiments show that these systems have significant oxygen absorption activity and can oxidize benzene to phenol in one step under normal temperature and pressure. The paper also discusses the relationship between structure and performance. On the basis of experiments, the tentative idea of ​​hydroxylation mechanism is put forward.