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目的:为了解TSGF-癌症快速检测试剂盒的敏感性、特异性及其在临床上的使用价值。方法:对临床恶性肿瘤病人59例、非恶性肿瘤病人78例、健康体检人268进行了血清中TSGF的含量测定与分析。结果:59例恶性肿瘤病人阳性率为71.2%;非恶性肿瘤病人78例阳性率为32.1%,可能由于非特异性血管生长因子干扰的假阳性现象有待于临床排除;268例健康体检人中阳性率为9.7%;明显低于恶性肿瘤病人的TSGF水平。TSGF总的敏感性71.2%,特异性90.3%,有效诊断率86.6%,作为恶性肿瘤标志物。结论:TSGF具备了较高的敏感性、特异性、广谱性。且由于操作简便,快速,无需特殊设备,可以用于人群普查以及病程监控等。
Objective: To understand the sensitivity, specificity and clinical value of TSGF-Cancer Rapid Test Kit. Methods: Serum levels of TSGF were measured and analyzed in 59 clinical malignant tumor patients, 78 non-malignant tumor patients and 268 healthy subjects. Results: The positive rate of malignant tumors in 59 cases was 71.2%. The positive rate of non-malignant tumors in 78 cases was 32.1%. The false positive phenomenon possibly due to non-specific vascular growth factor interference was to be excluded clinically. The positive rate of 268 healthy subjects 9.7%; significantly lower than the TSGF levels in patients with malignant tumors. TSGF 71.2% of the total sensitivity, specificity 90.3%, the effective diagnosis rate of 86.6%, as a malignant tumor marker. Conclusion: TSGF possesses high sensitivity, specificity and broad spectrum. And because of simple, fast, without special equipment, can be used for population census and course monitoring.