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血管紧张素II对慢性肾脏疾病进展具有重要作用 ,血管紧张素II的I型受体拮抗剂可阻断血管紧张素II的作用 ,有可能性成为一类新的肾脏保护药物。本文从动物实验和临床研究方面总结血管紧张素II受体拮抗剂对肾脏病的作用。
Angiotensin II plays an important role in the progression of chronic kidney disease. Type I receptor antagonists of angiotensin II block the action of angiotensin II, making it possible to become a new class of nephrotoxic drug. This article summarizes the effects of angiotensin II receptor antagonists on kidney disease from animal experiments and clinical studies.