苯的主要毒作用是对造血系统的损害。在工业中,人体长期接触低浓度苯可引起血液疾病,其中最明显的为再生障碍性贫血和白血病。本文论述苯在造血毒性研究方面的进展、代谢,以及苯引起血液疾病的发病机理。一、苯的毒性苯中毒的基本特征为全血细胞降低。有些人持续接触苯后可导致再生障碍性贫血,即有造血功能的骨髓组织被脂肪取代而引起的全血细胞减少;而另一些人表现为全血细胞减少,但骨髓增生,此为一种白血病前期状况。大量 The major toxic effect of benzene is on the hematopoietic system. In the industry, long-term exposure to low levels of benzene in humans can cause blood diseases, most notably aplastic anemia and leukemia. This article discusses the progress of benzene in hematopoietic toxicity studies, metabolism, and the pathogenesis of benzene-induced blood diseases. First, the toxicity of benzene The basic characteristics of benzene poisoning for pancytopenia. Persistent exposure to benzene in some people can lead to aplastic anemia, which is the pancytopenia caused by fat-replacement of bone marrow tissue with hematopoietic function; while others manifest as pancytopenia, but with myeloproliferation, a preleukemia situation. A lot