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目的 调查分析持续肾替代疗法 (CRRT)在儿科MODS中的治疗作用。 方法 回顾性总结 1998～ 2 0 0 1年我院PICU应用连续静静脉血液滤过和连续静静脉血液滤过透析 (CVVH/D)的临床资料。 结果 CVVH/D治疗 1个月～ 13岁的MODS患儿 12例 ,均存在 3个或 3个以上的脏器功能障碍。持续治疗时间 12～ 2 5 2h ,平均 ( 93 6± 83 9)h。 2例高血容量性肺水肿明显缓解 ,所有病例纠正了酸碱和水电解质紊乱。存活 5例 ,死亡 7例。 结论 CRRT具有清除体内过多液体和纠正酸碱、电解质紊乱的显著疗效 ,是一种PICU内可实行的安全而经济的治疗手段。
Objective To investigate the therapeutic effect of continuous renal replacement therapy (CRRT) in pediatric MODS. Methods The clinical data of continuous intravenous venous hemofiltration and continuous venous hemofiltration (CVVH / D) in PICU from 1998 to 2001 were retrospectively reviewed. Results Of the 12 children with MODS who were treated with CVVH / D for 1 month to 13 years, there were 3 or more organ dysfunction. The duration of continuous treatment was 12 ~ 25 2 hours, with an average of (93 6 ± 83 9) h. 2 cases of hypervolemic pulmonary edema significantly eased, and all cases corrected the acid-base and water-electrolyte imbalance. Survival in 5 cases, 7 deaths. Conclusion CRRT is a safe and economical treatment that can be practiced in PICU. It has the remarkable effect of clearing excess liquid in the body and correcting the disturbance of acid-base and electrolytes.