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抑素(inhibin)是睾丸曲精细管及卵巢颗粒细胞分泌的一种肽类激素,可选择性地抑制垂体前叶卵泡刺激素的分泌,调节卵巢滤泡的发育。抑素提纯的成功及生理作用的阐明,终于发现卵泡刺激素分泌调节的一个闭环式反馈调节通路。
Inhibin, a peptide hormone secreted by testicular seminiferous tubules and ovarian granulosa cells, selectively inhibits the secretion of anterior pituitary follicle stimulating hormone and regulates ovarian follicular development. The elucidation of the success and physiology of somatostatin purification finally found a closed-loop feedback regulatory pathway regulating the secretion of follicle-stimulating hormone.