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目的探讨消化道原发性恶性黑色素瘤的病理形态和临床表现,进一步提高对消化道原发性恶性黑色素瘤的组织起源认识和诊断水平。方法本文选取了部分诊断为消化道原发性恶性黑色素瘤病例,运用组织病理学和免疫化学等方法进行有效观察和分析。结果消化道原发性恶性黑色素瘤瘤细胞有梭形、瘤巨细胞和小痣细胞样等多种类型,呈巢状、束状、编织状和腺泡状等分布。结论消化道原发性恶性黑色素瘤是消化道罕见的高度恶性肿瘤,多发于高龄患者,应早诊早治。
Objective To investigate the pathological features and clinical manifestations of primary malignant melanoma in digestive tract and further improve the understanding of the origin and diagnosis of tissue origin in primary malignant melanoma of digestive tract. Methods Selected cases of primary malignant melanoma digestive tract cases, the use of histopathology and immunochemistry methods for effective observation and analysis. Results The primary malignant melanoma cells in the gastrointestinal tract were spindle-shaped, tumorous giant cells and small nevus cells and other types of cells were nested, bundles, braided and acinar distribution. Conclusions The primary malignant melanoma in gastrointestinal tract is a rare malignant tumor in the digestive tract. It is frequently found in elderly patients and should be diagnosed and treated early.